Article
Trends in Genotypic HIV-1 Antiretroviral Resistance between 2006 and 2012 in South African Patients Receiving First- and Second-Line Antiretroviral Treatment Regimens.
PloS one - 1 Jan 2013
Van Zyl Gert U, Liu Tommy F, Claassen Mathilda, Engelbrecht Susan, de Oliveira Tulio, Preiser Wolfgang, Wood Natasha T, Travers Simon, Shafer Robert W
Abstract excerpt
OBJECTIVES: South Africa's national antiretroviral (ARV) treatment program expanded in 2010 to include the nucleoside reverse transcriptase (RT) inhibitors (NRTI) tenofovir (TDF) for adults and abacavir (ABC) for children. We investigated the associated changes in genotypic drug resistance patterns in patients with first-line ARV treatment failure since the introduction of these drugs, and protease inhibitor (PI)...
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