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Article

MicroRNA-3666-induced suppression of SIRT7 inhibits the growth of non-small cell lung cancer cells

5 Sept 2016

Abstract excerpt

Sirtuin7 (SIRT7) plays an important role in many cancer types, but its function in non-small cell lung cancer (NSCLC) remains unclear. This study investigated the biological role and underlying mechanism of SIRT7 in NSCLC. Results showed that SIRT7 was highly expressed in NSCLC cell lines, as detected by real-time quantitative polymerase chain reaction and western blot analysis. SIRT7 knockdown by small...

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PMID: 27599551
DOI: 10.3892/or.2016.5063

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