Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of mitochondrial genomics in patients with non-alcoholic steatohepatitis (NASH).

BMC medical genetics - 5 Sept 2016

Mehta Rohini, Jeiran Kianoush, Koenig Aaron B, Otgonsuren Munkzhul, Goodman Zachary, Baranova Ancha, Younossi Zobair

Abstract excerpt

BACKGROUND: Visceral obesity and metabolic syndrome are commonly associated with non-alcoholic fatty liver disease (NAFLD). The progression of steatosis to NASH depends on a number of metabolic and patient-related factors. The mechanisms of genetic predisposition towards the development of NASH and related fibrosis remain unclear. In this study, our aim was to utilize mitotyping and identify mitochondrial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy
Share to Genome, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomics

Share to Lipase

Share to Membrane Proteins

Share to Mitochondria

Share to Non-alcoholic Fatty Liver Disease

Source

Open in PubMed Open full text

Identifiers

PMID: 27596100
DOI: 10.1186/s12881-016-0324-0
PMCID: PMC5011877

Genes

PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of mitochondrial genomics in patients with non-alcoholic steatohepatitis (NASH).PMID 27596100Read ↗

Mitochondrial haplogroup G is associated with nonalcoholic fatty liver disease, while haplogroup A mitigates the effects of PNPLA3.Semantic proximity Read ↗

Gene Variants Implicated in Steatotic Liver Disease: Opportunities for Diagnostics and TherapeuticsSemantic proximity Read ↗

Genetics and epigenetics of NAFLD and NASH: Clinical impact.Semantic proximity Read ↗

Association of single nucleotide polymorphism at PNPLA3 with fatty liver, steatohepatitis, and cirrhosis of liver.Semantic proximity Read ↗

The genetic backgrounds in nonalcoholic fatty liver disease.Semantic proximity Read ↗

The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease.Semantic proximity Read ↗

The effect of PNPLA3 polymorphism as gain in function mutation in the pathogenesis of non-alcoholic fatty liver disease.Semantic proximity Read ↗

Significance of genetic polymorphisms in patients with nonalcoholic fatty liver disease.Semantic proximity Read ↗

Nonalcoholic fatty liver disease risk and histologic severity are associated with genetic polymorphisms in children.Semantic proximity Read ↗

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.Semantic proximity Read ↗

A Perspective on Metabolic Syndrome and Nonalcoholic Fatty Liver Disease.Semantic proximity Read ↗

Genetic and epigenetic disease modifiers: non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.