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Article

The genetic backgrounds in nonalcoholic fatty liver disease.

Clinical journal of gastroenterology - 1 Apr 2018

Seko Yuya, Yamaguchi Kanji, Itoh Yoshito

Abstract excerpt

Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease worldwide. Nonalcoholic steatohepatitis (NASH), a severe form of NAFLD, can lead to hepatocellular carcinoma (HCC) and hepatic failure. The development and progression of NAFLD are determined by environmental and genetic factors. The effect of genetic factors has been demonstrated by familial studies, twin studies and several...

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Source

Identifiers

PMID: 29492830
DOI: 10.1007/s12328-018-0841-9

Genes

PNPLA3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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