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Article

Hypoxia-inducible factor 1α polymorphisms and early-stage cervical cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jan 2011

Kim Yun Hwan, Park In-Ae, Park Woong-Yang, Kim Jae Weon, Kim Seung Cheol, Park Noh-Hyun, Song Yong-Sang, Kang Soon-Beom

Abstract excerpt

BACKGROUND: Human papillomavirus can stabilize and induce hypoxia-inducible factor 1α (HIF-1α) protein, which is associated with diminished response to treatment and poor prognosis for cervical cancer. Hypoxia-inducible factor 1α polymorphisms (1772C>T and 1790G>A) in the N-terminal transactivation domain generate significantly increased transcriptional activity and have been linked to poor outcome in various...

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Identifiers

PMID: 21330825
DOI: 10.1097/IGC.0b013e318204f6e6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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