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Article

Functional spheroid organization of human salivary gland cells cultured on hydrogel-micropatterned nanofibrous microwells.

Acta biomaterialia - 1 Nov 2016

Shin Hyun-Soo, Kook Yun-Min, Hong Hye Jin, Kim Young-Mo, Koh Won-Gun, Lim Jae-Yol

Abstract excerpt

Development of a tissue-engineered, salivary bio-gland will benefit patients suffering from xerostomia due to loss of fluid-secreting acinar cells. This study was conducted to develop a bioengineering system to induce self-assembly of human parotid epithelial cells (hPECs) cultured on poly ethylene glycol (PEG) hydrogel-micropatterned polycaprolactone (PCL) nanofibrous microwells. Microwells were fabricated by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27592814
DOI: 10.1016/j.actbio.2016.08.058

Genes

AQP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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