Article
2D/3D buccal epithelial cell self-assembling as a tool for cell phenotype maintenance and fabrication of multilayered epithelial linings in vitro.
Biomedical materials (Bristol, England) - 19 Jul 2018
Zurina I M, Shpichka A I, Saburina I N, Kosheleva N V, Gorkun A A, Grebenik E A, Kuznetsova D S, Zhang D, Rochev Y A, Butnaru D V, Zharikova T M, Istranova E V, Zhang Y, Istranov L P, Timashev P S
Abstract excerpt
Maintaining the epithelial status of cells in vitro and fabrication of a multilayered epithelial lining is one of the key problems in the therapy using cell technologies. When cultured in a monolayer, epithelial cells change their phenotype from epithelial to epithelial-mesenchymal or mesenchymal that makes it difficult to obtain a sufficient number of cells in a 2D culture and to use them in tissue engineering....
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