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Article

450K Epigenome-Wide Scan Identifies Differential DNA Methylation in Newborns Related to Maternal Smoking during Pregnancy

25 Jul 2012

Abstract excerpt

BACKGROUND: Epigenetic modifications, such as DNA methylation, due to in utero exposures may play a critical role in early programming for childhood and adult illness. Maternal smoking is a major risk factor for multiple adverse health outcomes in children, but the underlying mechanisms are unclear. OBJECTIVE: We investigated epigenome-wide methylation in cord blood of newborns in relation to maternal smoking...

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PMID: 22851337
DOI: 10.1289/ehp.1205412

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