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DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring

10 Apr 2015

Abstract excerpt

BACKGROUND: We examined whether the effect of maternal smoking during pregnancy on birthweight of the offspring was mediated by smoking-induced changes to DNA methylation in cord blood. METHODS: First, we used cord blood of 129 Dutch children exposed to maternal smoking vs 126 unexposed to maternal and paternal smoking (53% male) participating in the GECKO Drenthe birth cohort. DNA methylation was measured using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25862628
DOI: 10.1093/ije/dyv048

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