Article
NKAIN2 functions as a novel tumor suppressor in prostate cancer.
Oncotarget - 27 Sept 2016
Mao Xueying, Luo Fei, Boyd Lara K, Zhou Bowei, Zhang Yanling, Stankiewicz Elzbieta, Marzec Jacek, Vasiljevic Natasa, Yu Yongwei, Feng Ninghan, Xu Jia, Lorincz Attila, Jiang Yong, Chelala Claude, Ren Guoping, Berney Daniel M, Zhao Shan-Chao, Lu Yong-Jie
Abstract excerpt
Recurrent chromosome breakpoints at 6q22.31, leading to truncation and potential loss-of-function of the NKAIN2 gene, in Chinese prostate cancer patients were previously identified. In this study we investigated genomic, methylation and expression changes of NKAIN2 in a large number of prostate cancer samples and determined its functional role in prostate cancer cells. Fluorescence in situ hybridization analysis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
