Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence of epistatic interaction between DPP4 and CCR6 in patients with rheumatoid arthritis.

Rheumatology (Oxford, England) - 1 Dec 2016

Leng Rui-Xue, Liu Juan, Yang Xiao-Ke, Wang Bin, Zhang Chao, Tao Sha-Sha, Wang De-Guang, Li Xiao-Mei, Li Xiang-Pei, Pan Hai-Feng, Ye Dong-Qing

Abstract excerpt

OBJECTIVE: A recent genome-wide association study identified that genetic variants in DPP4 and CCR6 are connected with a risk of RA in the Han Chinese population. The aim of this study was to estimate the epistatic interaction between DPP4 and CCR6 in RA. METHODS: Two single-nucleotide polymorphisms identified in a Han Chinese genome-wide association study (rs12617656 in DPP4, rs1854853 in CCR6) were genotyped....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Age of Onset
Share to Arthritis, Rheumatoid
Share to Asian People
Share to Dipeptidyl Peptidase 4
Share to Epistasis, Genetic
Share to Genome-Wide Association Study
Share to Lupus Erythematosus, Systemic
Share to Th17 Cells

Source

Identifiers

PMID: 27587881
DOI: 10.1093/rheumatology/kew315

Genes

CCR6
DPP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Evidence of epistatic interaction between DPP4 and CCR6 in patients with rheumatoid arthritis.PMID 27587881Read ↗

Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans.Semantic proximity Read ↗

Immunochip Analyses of Epistasis in Rheumatoid Arthritis Confirm Multiple Interactions within MHC and Suggest Novel Non-MHC Epistatic Signals.Semantic proximity Read ↗

Epistasis amongst PTPN2 and genes of the vitamin D pathway contributes to risk of juvenile idiopathic arthritis.Semantic proximity Read ↗

Identification of epistatic SNP combinations in rheumatoid arthritis using LAMPLINK and Japanese cohorts.Semantic proximity Read ↗

Evidence of epistasis between TNFRSF14 and TNFRSF6B polymorphisms in patients with rheumatoid arthritis.Semantic proximity Read ↗

Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis.Semantic proximity Read ↗

Epistatic interaction between BANK1 and BLK in rheumatoid arthritis: results from a large trans-ethnic meta-analysis.Semantic proximity Read ↗

Association between PADI4 and rheumatoid arthritis: a meta-analysis.Semantic proximity Read ↗

Epistatic interaction between PKD2 and ABCG2 influences the pathogenesis of hyperuricemia and gout.Semantic proximity Read ↗

Epistatic interactions between genomic regions containing the COL1A1 gene and genes regulating osteoclast differentiation may influence femoral neck bone mineral density.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.