Article
Optimal Design of Low-Density SNP Arrays for Genomic Prediction: Algorithm and Applications.
PloS one - 1 Jan 2016
Wu Xiao-Lin, Xu Jiaqi, Feng Guofei, Wiggans George R, Taylor Jeremy F, He Jun, Qian Changsong, Qiu Jiansheng, Simpson Barry, Walker Jeremy, Bauck Stewart
Abstract excerpt
Low-density (LD) single nucleotide polymorphism (SNP) arrays provide a cost-effective solution for genomic prediction and selection, but algorithms and computational tools are needed for the optimal design of LD SNP chips. A multiple-objective, local optimization (MOLO) algorithm was developed for design of optimal LD SNP chips that can be imputed accurately to medium-density (MD) or high-density (HD) SNP...
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