Article
Imputation of genotypes with low-density chips and its effect on reliability of direct genomic values in Dutch Holstein cattle.
Journal of dairy science - 1 Feb 2012
Mulder H A, Calus M P L, Druet T, Schrooten C
Abstract excerpt
Genomic selection using 50,000 single nucleotide polymorphism (50k SNP) chips has been implemented in many dairy cattle breeding programs. Cheap, low-density chips make genotyping of a larger number of animals cost effective. A commonly proposed strategy is to impute low-density genotypes up to 50,000 genotypes before predicting direct genomic values (DGV). The objectives of this study were to investigate the...
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