Phase II Weekly Vinblastine for Chemotherapy-Naïve Children With Progressive Low-Grade Glioma: A Canadian Pediatric Brain Tumor Consortium Study.

doi:10.1200/JCO.2016.68.1585

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Article

Phase II Weekly Vinblastine for Chemotherapy-Naïve Children With Progressive Low-Grade Glioma: A Canadian Pediatric Brain Tumor Consortium Study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Oct 2016

Lassaletta Alvaro, Scheinemann Katrin, Zelcer Shayna M, Hukin Juliette, Wilson Beverley A, Jabado Nada, Carret Anne Sophie, Lafay-Cousin Lucie, Larouche Valerie, Hawkins Cynthia E, Pond Gregory Russell, Poskitt Ken, Keene Daniel, Johnston Donna L, Eisenstat David D, Krishnatry Rahul, Mistry Matthew, Arnoldo Anthony, Ramaswamy Vijay, Huang Annie, Bartels Ute, Tabori Uri, Bouffet Eric

Abstract excerpt

Purpose Vinblastine monotherapy has shown promising activity and a low-toxicity profile in patients with pediatric low-grade glioma (PLGG) who experienced treatment failure after initial treatment with chemotherapy and/or radiation. The aim of this study was to assess the activity of vinblastine in therapy-naïve children. Patients and Methods Patients < 18 years old with unresectable and/or progressive...

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PMID: 27573663
DOI: 10.1200/JCO.2016.68.1585

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BRAF

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