Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ceramide and polyunsaturated phospholipids are strongly reduced in human hepatocellular carcinoma.

Biochimica et biophysica acta - 1 Nov 2016

Krautbauer Sabrina, Meier Elisabeth M, Rein-Fischboeck Lisa, Pohl Rebekka, Weiss Thomas S, Sigruener Alexander, Aslanidis Charalampos, Liebisch Gerhard, Buechler Christa

Abstract excerpt

Lipid composition affects membrane function, cell proliferation and cell death and is changed in cancer tissues. Hepatocellular carcinoma (HCC) is an aggressive cancer and this study aimed at a comprehensive characterization of hepatic and serum lipids in human HCC. Cholesteryl ester were higher in tumorous tissues (TT) compared to adjacent non-tumorous tissues (NT). Free cholesterol exerting cytotoxic effects...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Ceramides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fatty Acids, Unsaturated

Share to Fatty Liver

Share to Liver Neoplasms

Share to Phospholipids

Share to Principal Component Analysis

Share to Sphingomyelins

Source

Identifiers

PMID: 27570113
DOI: 10.1016/j.bbalip.2016.08.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ceramide and polyunsaturated phospholipids are strongly reduced in human hepatocellular carcinoma.PMID 27570113Read ↗

Lipid alterations in chronic liver disease and liver cancerSemantic proximity Read ↗

Bilayer Forming Phospholipids as Targets for Cancer TherapySemantic proximity Read ↗

The altered lipidome of hepatocellular carcinomaSemantic proximity Read ↗

Update on Glycosphingolipids Abundance in Hepatocellular CarcinomaSemantic proximity Read ↗

Hepatocellular Carcinoma Overcomes Lipid Depletion by Utilizing Serine for Phospholipid Synthesis and Enhanced SurvivalSemantic proximity Read ↗

Ceramides and ceramide synthases in cancer: Focus on apoptosis and autophagySemantic proximity Read ↗

Serum Ceramide Species Are Associated with Liver Cirrhosis and Viral Genotype in Patients with Hepatitis C Infection.Semantic proximity Read ↗

Occult infection with hepatitis B virus PreS variants synergistically promotes hepatocellular carcinoma development in a high-fat diet context by generating abnormal ceramides.Semantic proximity Read ↗

PEMT Mediates Hepatitis C Virus-Induced Steatosis, Explains Genotype-Specific Phenotypes and Supports Virus Replication.Semantic proximity Read ↗

Elevated plasma sphingomyelin (d18:1/22:0) is closely related to hepatic steatosis in patients with chronic hepatitis C virus infection.Semantic proximity Read ↗

A Lipidomic Signature Complements Stemness Features Acquisition in Liver Cancer CellsSemantic proximity Read ↗

Tumor suppressive functions of ceramide: evidence and mechanismsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.