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Mapping the Cell-Surface N-Glycoproteome of Human Hepatocytes Reveals Markers for Selecting a Homogeneous Population of iPSC-Derived Hepatocytes.

Stem cell reports - 13 Sept 2016

Mallanna Sunil K, Cayo Max A, Twaroski Kirk, Gundry Rebekah L, Duncan Stephen A

Abstract excerpt

When comparing hepatic phenotypes between iPSC-derived hepatocyte-like cells from different liver disease patients, cell heterogeneity can confound interpretation. We proposed that homogeneous cell populations could be generated by fluorescence-activated cell sorting (FACS). Using cell-surface capture proteomics, we identified a total of 300 glycoproteins on hepatocytes. Analyses of the expression profiles during...

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Identifiers

PMID: 27569060
DOI: 10.1016/j.stemcr.2016.07.016
PMCID: PMC5032032

Genes

AADAC
CLRN3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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