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Article

DZIP3 is a key factor to stratify IDH1 wild-type lower-grade gliomas

21 Nov 2020

Abstract excerpt

BACKGROUND: Malignant glioma is the most common form of primary malignant brain cancer. Heterogeneity is the hallmark of glioma. DAZ-interacting zinc finger 3 (DZIP3), acts as an RNA-binding RING-type ubiquitin ligase; however, its function in glioma is yet unclear. RESULTS: wild-type lower-grade gliomas could be divided into two groups with different survival time. CONCLUSION: In conclusion, the loss of DZIP3...

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PMID: 33229627
DOI: 10.18632/aging.103817

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