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Article

Molecular characterization of lipoamide dehydrogenase gene in Trypanosoma cruzi populations susceptible and resistant to benznidazole.

Experimental parasitology - 1 Nov 2016

Dos Santos Paula F, Moreira Douglas S, Baba Elio H, Volpe Caroline M O, Ruiz Jerônimo C, Romanha Alvaro J, Murta Silvane M F

Abstract excerpt

Lipoamide dehydrogenase (LipDH) is a flavin-containing disulfide oxidoreductase from the same group of thioredoxin reductase, glutathione reductase and trypanothione reductase. This enzyme is found in the mitochondria of all aerobic organisms where it takes part in at least three important multienzyme complexes from the citric acid cycle. In this study, we performed a phylogenetic analysis comparing the amino...

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PMID: 27567984
DOI: 10.1016/j.exppara.2016.08.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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