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Article

In vitro susceptibility of Trypanosoma cruzi discrete typing units (DTUs) to benznidazole: A systematic review and meta-analysis.

PLoS neglected tropical diseases - 1 Mar 2021

Vela Andrea, Coral-Almeida Marco, Sereno Denis, Costales Jaime A, Barnabé Christian, Brenière Simone Frédérique

Abstract excerpt

BACKGROUND: Chagas disease, a neglected tropical disease endemic to Latin America caused by the parasite Trypanosoma cruzi, currently affects 6-7 million people and is responsible for 12,500 deaths each year. No vaccine exists at present and the only two drugs currently approved for the treatment (benznidazole and nifurtimox), possess serious limitations, including long treatment regimes, undesirable side...

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Identifiers

PMID: 33750958
DOI: 10.1371/journal.pntd.0009269
PMCID: PMC8016252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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