Article
Differential IgM expression distinguishes two types of pediatric Burkitt lymphoma in mouse and human.
Oncotarget - 27 Sept 2016
Eason Anthony B, Sin Sang-Hoon, Lin Carolina, Damania Blossom, Park Steven, Fedoriw Yuri, Bacchi Carlos E, Dittmer Dirk P
Abstract excerpt
Endemic Burkitt lymphoma (eBL) is primarily a childhood cancer in parts of Africa and Brazil. Classic studies describe eBL as a homogeneous entity based on t(8;14) IgH-Myc translocation and clinical response to cytotoxic therapy. By contrast, sporadic BL (sBL) in Western countries is considered more heterogeneous, and affects both children and adults. It is overrepresented in AIDS patients. Unlike diffuse large B...
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