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Article

Beneficial effects of increased lysozyme levels in Alzheimer's disease modelled in Drosophila melanogaster.

The FEBS journal - 1 Oct 2016

Sandin Linnea, Bergkvist Liza, Nath Sangeeta, Kielkopf Claudia, Janefjord Camilla, Helmfors Linda, Zetterberg Henrik, Blennow Kaj, Li Hongyun, Nilsberth Camilla, Garner Brett, Brorsson Ann-Christin, Kågedal Katarina

Abstract excerpt

Genetic polymorphisms of immune genes that associate with higher risk to develop Alzheimer's disease (AD) have led to an increased research interest on the involvement of the immune system in AD pathogenesis. A link between amyloid pathology and immune gene expression was suggested in a genome-wide gene expression study of transgenic amyloid mouse models. In this study, the gene expression of lysozyme, a major...

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Identifiers

PMID: 27562772
DOI: 10.1111/febs.13830
PMCID: PMC5132093

Genes

BACE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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