Article
Identification of a Bipolar Disorder Vulnerable Gene CHDH at 3p21.1.
Molecular neurobiology - 1 Sept 2017
Chang Hong, Li Lingyi, Peng Tao, Grigoroiu-Serbanescu Maria, Bergen Sarah E, Landén Mikael, Hultman Christina M, Forstner Andreas J, Strohmaier Jana, Hecker Julian, Schulze Thomas G, Müller-Myhsok Bertram, Reif Andreas, Mitchell Philip B, Martin Nicholas G, Cichon Sven, Nöthen Markus M, Jamain Stéphane, Leboyer Marion, Bellivier Frank, Etain Bruno, Kahn Jean-Pierre, Henry Chantal, Rietschel Marcella, Xiao Xiao, Li Ming
Abstract excerpt
Genome-wide analysis (GWA) is an effective strategy to discover extreme effects surpassing genome-wide significant levels in studying complex disorders; however, when sample size is limited, the true effects may fail to achieve genome-wide significance. In such case, there may be authentic results among the pools of nominal candidates, and an alternative approach is to consider nominal candidates but are...
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