Article
Cross-disorder analysis of bipolar risk genes: further evidence of DGKH as a risk gene for bipolar disorder, but also unipolar depression and adult ADHD.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Sept 2011
Weber Heike, Kittel-Schneider Sarah, Gessner Alexandra, Domschke Katharina, Neuner Maria, Jacob Christian P, Buttenschon Henriette N, Boreatti-Hümmer Andrea, Volkert Julia, Herterich Sabine, Baune Bernhard T, Gross-Lesch Silke, Kopf Juliane, Kreiker Susanne, Nguyen Thuy Trang, Weissflog Lena, Arolt Volker, Mors Ole, Deckert Jürgen, Lesch Klaus-Peter, Reif Andreas
Abstract excerpt
Recently, several genome-wide association studies (GWAS) on bipolar disorder (BPD) suggested novel risk genes. However, only few of them were followed up and further, the specificity of these genes is even more elusive. To address these issues, we genotyped SNPs in ANK3, CACNA1C, CMTM8, DGKH, EGFR, and NPAS3, which were significantly associated with BPD in previous GWAS, in a sample of 380 BPD patients....
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