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Article

Candidate risk genes for bipolar disorder are highly conserved during evolution and highly interconnected.

Bipolar disorders - 1 Jun 2021

Franklin Claire, Dwyer Donard S

Abstract excerpt

OBJECTIVES: Bipolar disorder (BPD) is a highly heritable psychiatric disorder whose genetic complexity and pathogenetic mechanisms are still being unraveled. The main goal of this work was to characterize BPD risk-gene candidates (identified by Nurnberger et al., JAMA Psychiatry 71:657, 2014, and Stahl et al., Nat. Genet. 51:793, 2019) with respect to their evolutionary conservation, associated phenotypes, and...

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PMID: 32959503
DOI: 10.1111/bdi.12996

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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