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Article

Modification of Pulsed Electric Field Conditions Results in Distinct Activation Profiles of Platelet-Rich Plasma.

PloS one - 1 Jan 2016

Frelinger Andrew L, Gerrits Anja J, Garner Allen L, Torres Andrew S, Caiafa Antonio, Morton Christine A, Berny-Lang Michelle A, Carmichael Sabrina L, Neculaes V Bogdan, Michelson Alan D

Abstract excerpt

BACKGROUND: Activated autologous platelet-rich plasma (PRP) used in therapeutic wound healing applications is poorly characterized and standardized. Using pulsed electric fields (PEF) to activate platelets may reduce variability and eliminate complications associated with the use of bovine thrombin. We previously reported that exposing PRP to sub-microsecond duration, high electric field (SMHEF) pulses generates...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27556645
DOI: 10.1371/journal.pone.0160933
PMCID: PMC4996457

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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