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Article

Activated platelet supernatant can augment the angiogenic potential of human peripheral blood stem cells mobilized from bone marrow by G-CSF.

Journal of molecular and cellular cardiology - 1 Oct 2014

Kang Jeehoon, Hur Jin, Kang Jin-A, Yun Ji-Yeon, Choi Jae-Il, Ko Seung Bum, Lee Choon-Soo, Lee Jaewon, Han Jung-Kyu, Kim Hyun Kyung, Kim Hyo-Soo

Abstract excerpt

Platelets not only play a role in hemostasis, but they also promote angiogenesis and tissue recovery by releasing various cytokines and making an angiogenic milieu. Here, we examined autologous 'activated platelet supernatant (APS)' as a priming agent for stem cells; thereby enhance their pro-angiogenic potential and efficacy of stem cell-based therapy for ischemic diseases. The mobilized peripheral blood stem...

Read the complete abstract on PubMed

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Share to Granulocyte Colony-Stimulating Factor
Share to Hematopoietic Stem Cell Mobilization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Human Umbilical Vein Endothelial Cells

Share to Neovascularization, Physiologic

Share to Paracrine Communication

Share to Platelet Activation

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Source

Identifiers

PMID: 25016235
DOI: 10.1016/j.yjmcc.2014.06.019

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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