Article
Genetic Association for P2X7R rs3751142 and CARD8 rs2043211 Polymorphisms for Susceptibility of Gout in Korean Men: Multi-Center Study.
Journal of Korean medical science - 1 Oct 2016
Lee Sung Won, Lee Shin Seok, Oh Dong Ho, Park Dong Jin, Kim Hyun Sook, Choi Jung Ran, Chae Soo Cheon, Yun Ki Jung, Chung Won Tae, Choe Jung Yoon, Kim Seong Kyu
Abstract excerpt
The aim of this study was to determine the association between P2X7R rs3751142 and CARD8 rs2043211 polymorphisms and gout susceptibility in male Korean subjects. This study enrolled a total of 242 male patients with gout and 280 healthy controls. The polymorphisms of two individual genes including rs3751142(C>A) in the P2X7R gene and rs2043211(A>T) in the CARD8 gene were assessed using Taq-Man analysis....
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