Tissue-resident memory T cell signatures from single-cell analysis associated with better melanoma prognosis

Abstract excerpt

Tissue-resident memory T cells (T RM ) are a specialized T cell population residing in peripheral tissues. The presence and potential impact of T RM in the tumor immune microenvironment (TIME) remain to be elucidated. Here, we systematically investigated the relationship between T RM and melanoma TIME based on multiple clinical single-cell RNA-seq datasets and developed signatures indicative of T RM infiltration....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to CAR-T cell therapy research
• Share to Single-cell and spatial transcriptomics
• Share to T-cell and B-cell Immunology