Article
Reevaluation of RINT1 as a breast cancer predisposition gene.
Breast cancer research and treatment - 1 Sept 2016
Li Na, Thompson Ella R, Rowley Simone M, McInerny Simone, Devereux Lisa, Goode David, Wong-Brown Michelle W, Scott Rodney J, Trainer Alison H, Gorringe Kylie L, James Paul A, Campbell Ian G
Abstract excerpt
Rad50 interactor 1 (RINT1) has recently been reported as an intermediate-penetrance (odds ratio 3.24) breast cancer susceptibility gene, as well as a risk factor for Lynch syndrome. The coding regions and exon-intron boundaries of RINT1 were sequenced in 2024 familial breast cancer cases previously tested negative for BRCA1, BRCA2, and PALB2 mutations and 1886 population-matched cancer-free controls using...
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