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Article

Epigenetic contribution of the myosin light chain kinase gene to the risk for acute respiratory distress syndrome.

Translational research : the journal of laboratory and clinical medicine - 1 Feb 2017

Szilágyi Keely L, Liu Cong, Zhang Xu, Wang Ting, Fortman Jeffrey D, Zhang Wei, Garcia Joe G N

Abstract excerpt

Acute respiratory distress syndrome (ARDS) is a devastating clinical syndrome with a considerable case fatality rate (∼30%-40%). Health disparities exist with African descent (AD) subjects exhibiting greater mortality than European descent (ED) individuals. Myosin light chain kinase is encoded by MYLK, whose genetic variants are implicated in ARDS pathogenesis and may influence ARDS mortality. As baseline...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27543902
DOI: 10.1016/j.trsl.2016.07.020
PMCID: PMC5253100

Genes

MYLK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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