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Article

Identification of novel single nucleotide polymorphisms associated with acute respiratory distress syndrome by exome-seq.

PloS one - 1 Jan 2014

Shortt Katherine, Chaudhary Suman, Grigoryev Dmitry, Heruth Daniel P, Venkitachalam Lakshmi, Zhang Li Q, Ye Shui Q

Abstract excerpt

Acute respiratory distress syndrome (ARDS) is a lung condition characterized by impaired gas exchange with systemic release of inflammatory mediators, causing pulmonary inflammation, vascular leak and hypoxemia. Existing biomarkers have limited effectiveness as diagnostic and therapeutic targets. To identify disease-associating variants in ARDS patients, whole-exome sequencing was performed on 96 ARDS patients,...

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Identifiers

PMID: 25372662
DOI: 10.1371/journal.pone.0111953
PMCID: PMC4221189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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