Article
Silica microbeads capture fetal nucleated red blood cells for noninvasive prenatal testing of fetal ABO genotype.
Electrophoresis - 1 Jun 2020
Cheng Lin, Wei Xiaoyun, Wang Zixiang, Feng Chun, Gong Qing, Fu Yourong, Zhao Xingzhong, Zhang Yuanzhen
Abstract excerpt
ABO hemolytic disease of the newborn (ABO-HDN), which may cause neonatal jaundice and polycythemia, or even stillbirth or neonatal death, is widespread in China. Prenatal testing for the fetal ABO blood group can reduce unnecessary concerns or ensure prompt treatment. Herein, we presented a method to employ high-density silica microbeads (SiO2 MBs) for capturing fetal nucleated red blood cells (fnRBCs) in...
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