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Article

Activation of DNA damage repair pathways by murine polyomavirus.

Virology - 1 Oct 2016

Heiser Katie, Nicholas Catherine, Garcea Robert L

Abstract excerpt

Nuclear replication of DNA viruses activates DNA damage repair (DDR) pathways, which are thought to detect and inhibit viral replication. However, many DNA viruses also depend on these pathways in order to optimally replicate their genomes. We investigated the relationship between murine polyomavirus (MuPyV) and components of DDR signaling pathways including CHK1, CHK2, H2AX, ATR, and DNAPK. We found that...

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Identifiers

PMID: 27529739
DOI: 10.1016/j.virol.2016.07.028
PMCID: PMC5026627

Genes

ATR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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