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How human papillomavirus (HPV) targets DNA repair pathways for viral replication: from guardian to accomplice

27 Jan 2025

Abstract excerpt

SUMMARYHuman papillomaviruses (HPVs) are small DNA viruses that are responsible for significant disease burdens worldwide, including cancers of the cervix, anogenital tract, and oropharynx. HPVs infect stratified epithelia at a variety of body locations and link their productive life cycles to the differentiation of the host cell. These viruses have evolved sophisticated mechanisms to exploit cellular pathways,...

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PMID: 39868790
DOI: 10.1128/mmbr.00153-23

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