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Article

Teratozoospermia and asthenozoospermia are associated with specific epigenetic signatures

16 Aug 2016

Abstract excerpt

Semen analysis is commonly used as a tool to assess the fertility potential of a male, despite its relatively low predictive power. In this study, we have assessed associations between semen analysis findings (low count, low motility, low viability, poor sperm penetration assay results, poor morphology, and increased DNA damage) and DNA methylation patterns in mature spermatozoa. DNA methylation patterns in the...

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PMID: 27529490
DOI: 10.1111/andr.12231

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