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Sperm global <scp>DNA</scp> methylation level: association with semen parameters and genome integrity

1 Mar 2015

Abstract excerpt

Sperm DNA methylation abnormalities have been detected in oligozoospermic men. However, the association between sperm DNA methylation defects, sperm parameters and sperm DNA, and chromatin integrity remains poorly understood. This study was designed to clarify this issue. We recruited a cohort of 92 men (62 normozoospermic and 30 oligoasthenozoospermic) presenting for infertility evaluation during a 1-year...

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PMID: 25755112
DOI: 10.1111/andr.12001

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