Article
Does COX1 gene polymorphism (A842G/C50T) influence peptic ulcer bleeding in Indian patients?.
Tropical gastroenterology : official journal of the Digestive Diseases Foundation - 1 Jan 2000
Santhosh S, Simon Ebby George, Joseph A J, Dutta Amit Kumar, Chowdhury Sudipta Dhar, Kurien Reuben Thomas, Chacko Ashok
Abstract excerpt
This is a pilot study to test the hypothesis that polymorphisms that may be linked to cyclooxygenase production may affect the likelihood and the nature of bleeding in patients with ulcer disease. Of the two polymorphism that have previously been studied for links we chose the A842G polymorphims. Of the 50 patients with ulcer bleeding who were studied, 8 had a heterozygous polymorphisms and 42 had the normal...
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