Article
Impact of blood type, functional polymorphism (T-1676C) of the COX-1 gene promoter and clinical factors on the development of peptic ulcer during cardiovascular prophylaxis with low-dose aspirin.
BioMed research international - 1 Jan 2014
Wang Pin-Yao, Chen Hsiu-Ping, Chen Angela, Tsay Feng-Woei, Lai Kwok-Hung, Kao Sung-Shuo, Chen Wen-Chi, Kuo Chao-Hung, Peng Nan-Jing, Tseng Hui-Hwa, Hsu Ping-I
Abstract excerpt
AIMS: To investigate the impact of blood type, functional polymorphism (T-1676C) of the COX-1 gene promoter, and clinical factors on the development of peptic ulcer during cardiovascular prophylaxis with low-dose aspirin. METHODS: In a case-control study including 111 low-dose aspirin users with peptic ulcers and 109 controls (asymptomatic aspirin users), the polymorphism (T-1676C) of the COX-1 gene promoter was...
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