Article
Loop B serine of a plasma membrane aquaporin type PIP2 but not PIP1 plays a key role in pH sensing.
Biochimica et biophysica acta - 1 Nov 2016
Yaneff Agustín, Sigaut Lorena, Gómez Natalia, Aliaga Fandiño Cecilia, Alleva Karina, Pietrasanta Lía Isabel, Amodeo Gabriela
Abstract excerpt
In the plant kingdom, the plasma membrane intrinsic aquaporins (PIPs) constitute a highly conserved group of water channels with the capacity of rapidly adjusting the water permeability (Pf) of a cell by a gating response. Most evidence regarding this mechanism was obtained by different biophysical approaches including the crystallization of a Spinaca olaracea PIP2 aquaporin (SoPIP2;1) in an open and close...
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