Article
Single amino acid substitutions in the selectivity filter render NbXIP1;1α aquaporin water permeable.
BMC plant biology - 9 Mar 2017
Ampah-Korsah Henry, Sonntag Yonathan, Engfors Angelica, Kirscht Andreas, Kjellbom Per, Johanson Urban
Abstract excerpt
BACKGROUND: Aquaporins (AQPs) are integral membrane proteins that facilitate transport of water and/or other small neutral solutes across membranes in all forms of life. The X Intrinsic Proteins (XIPs) are the most recently recognized and the least characterized aquaporin subfamily in higher plants. XIP1s have been shown to be impermeable to water but permeable to boric acid, glycerol, hydrogen peroxide and urea....
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