Article
Identification of a residue in helix 2 of rice plasma membrane intrinsic proteins that influences water permeability.
The Journal of biological chemistry - 31 Dec 2010
Zhang Minhua, Lü Shouqin, Li Guowei, Mao Zhilei, Yu Xin, Sun Weining, Tang Zhangcheng, Long Mian, Su Weiai
Abstract excerpt
Molecular selection, ion exclusion, and water permeation are well known regulatory mechanisms in aquaporin. Water permeability was found to be diverse in different subgroups of plasma membrane intrinsic proteins (PIPs), even though the residues surrounding the water holes remained the same across the subgroups. Upon homology modeling and structural comparison, a conserved Ala/Ile(Val) residue difference was...
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