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Zika Virus–Induced Antibody Response Enhances Dengue Virus Serotype 2 Replication In Vitro

11 Aug 2016

Abstract excerpt

Zika virus has emerged in the Americas, where dengue virus is endemic. Among the 4 serotypes of dengue virus, antibody-dependent enhancement is thought to enhance viral replication and disease severity. Reports suggest that anti-dengue virus antibody may enhance Zika virus replication. We investigated whether Zika virus antibodies enhance dengue virus replication, by exposing C57Bl/6 mice to Zika virus....

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PMID: 27521359
DOI: 10.1093/infdis/jiw377

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