Article
Diversities of Calreticulin Gene Mutations in Macedonian Patients With Essential Thrombocythemia.
Clinical lymphoma, myeloma & leukemia - 1 Aug 2016
Panovska-Stavridis Irina, Eftimov Aleksandar, Ivanovski Martin, Stojanovic Aleksandar, Georgievski Borce, Cevreska Lidija, Dimovski Aleksandar J
Abstract excerpt
BACKGROUND: Acquired calreticulin (CALR) gene mutations are one of the molecular hallmarks of essential thrombocythemia (ET). It has been suggested that patients with ET with CALR mutations are associated with a distinct clinical phenotype. PATIENTS AND METHODS: We evaluated the clinical and molecular features of 150 patients with ET followed over a period of 15 years. The screening for the presence of...
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