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Article

CALR-ETdb, the database of calreticulin variants diversity in essential thrombocythemia

14 Jan 2021

Abstract excerpt

Essential thrombocythemia (ET) is a blood cancer defined by a strong increase of platelet numbers. A quarter of patients suffering from ET show mutations in the last exon of calreticulin (CALR) gene. Two variants named type 1 and type 2 represent 85% of these patients. However, a large number of other variants have been determined. In this study, we have compiled variants taken from COSMIC database and literature...

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PMID: 33444113
DOI: 10.1080/09537104.2020.1869712

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