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Article

Phenotypic characterization and clinical outcome in ampullary adenocarcinoma.

Journal of surgical oncology - 1 Jul 2016

Asano Eisuke, Okano Keiichi, Oshima Minoru, Kagawa Seiko, Kushida Yoshio, Munekage Masaya, Hanazaki Kazuhiro, Watanabe Jota, Takada Yasutsugu, Ikemoto Tetsuya, Shimada Mitsuo, Suzuki Yasuyuki

Abstract excerpt

BACKGROUND: Although various features of ampullary adenocarcinoma have been reported, the impact of genetic alterations and rare subtypes on clinical outcome remains unclear. METHODS: We determined the expression of proteins, including MUC1, MUC2, p53, p16, Smad/Dpc4, and β-catenin, and genetic mutations such as KRAS, BRAF, and GNAS mutations in 69 patients with ampullary adenocarcinoma to clarify their...

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Source

Identifiers

PMID: 27132476
DOI: 10.1002/jso.24274

Genes

KRAS
MUC1
MUC2
BRAF
GNAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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