Article
Expansion of highly activated invariant natural killer T cells with altered phenotype in acute dengue infection.
Clinical and experimental immunology - 1 Aug 2016
Kamaladasa A, Wickramasinghe N, Adikari T N, Gomes L, Shyamali N L A, Salio M, Cerundolo V, Ogg G S, Malavige G Neelika
Abstract excerpt
Invariant natural killer T (iNKT) cells are capable of rapid activation and production of cytokines upon recognition of antigenic lipids presented by CD1d molecules. They have been shown to play a significant role in many viral infections and were observed to be highly activated in patients with acute dengue infection. In order to characterize further their role in dengue infection, we investigated the proportion...
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