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Article

Polymorphisms in androgen metabolism genes AR, CYP1B1, CYP19, and SRD5A2and prostate cancer risk and aggressiveness in Bulgarian patients.

Turkish journal of medical sciences - 19 Apr 2016

Kachakova Darina, Mitkova Atanaska, Popov Elenko, Beltcheva Olga, Vlahova Alexandrina, Dikov Tihomir, Christova Svetlana, Mitev Vanio, Slavov Chavdar, Kaneva Radka

Abstract excerpt

BACKGROUND/AIM: The aim of our study was to elucidate the role of polymorphisms in AR, CYP1B1, CYP19, and SRD5A2 genes for prostate cancer (PC) development in Bulgarian patients. MATERIALS AND METHODS: We genotyped 246 PC patients and 261 controls (155 with benign prostate hyperplasia and 107 healthy population controls) using direct sequencing, PCR-RFLP, SSCP, and fragment analysis. RESULTS: The allele and...

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Identifiers

PMID: 27513235
DOI: 10.3906/sag-1501-124

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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