Article
The effect of the apolipoprotein E genotype on response to personalized dietary advice intervention: findings from the Food4Me randomized controlled trial.
The American journal of clinical nutrition - 1 Sept 2016
Fallaize Rosalind, Celis-Morales Carlos, Macready Anna L, Marsaux Cyril Fm, Forster Hannah, O'Donovan Clare, Woolhead Clara, San-Cristobal Rodrigo, Kolossa Silvia, Hallmann Jacqueline, Mavrogianni Christina, Surwillo Agnieszka, Livingstone Katherine M, Moschonis George, Navas-Carretero Santiago, Walsh Marianne C, Gibney Eileen R, Brennan Lorraine, Bouwman Jildau, Grimaldi Keith, Manios Yannis, Traczyk Iwona, Drevon Christian A, Martinez J Alfredo, Daniel Hannelore, Saris Wim Hm, Gibney Michael J, Mathers John C, Lovegrove Julie A
Abstract excerpt
BACKGROUND: The apolipoprotein E (APOE) risk allele (ɛ4) is associated with higher total cholesterol (TC), amplified response to saturated fatty acid (SFA) reduction, and increased cardiovascular disease. Although knowledge of gene risk may enhance dietary change, it is unclear whether ɛ4 carriers would benefit from gene-based personalized nutrition (PN). OBJECTIVES: The aims of this study were to 1) investigate...
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