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Article

A Putative Association of a Single Nucleotide Polymorphism in GPR126 with Aggressive Periodontitis in a Japanese Population.

PloS one - 1 Jan 2016

Kitagaki Jirouta, Miyauchi Shizuka, Asano Yoshihiro, Imai Atsuko, Kawai Shinji, Michikami Ikumi, Yamashita Motozo, Yamada Satoru, Kitamura Masahiro, Murakami Shinya

Abstract excerpt

Periodontitis is an inflammatory disease causing loss of tooth-supporting periodontal tissue. Disease susceptibility to the rapidly progressive form of periodontitis, aggressive periodontitis (AgP), appears to be influenced by genetic risk factors. To identify these in a Japanese population, we performed whole exome sequencing of 41 unrelated generalized or localized AgP patients. We found that AgP is putatively...

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PMID: 27509131
DOI: 10.1371/journal.pone.0160765
PMCID: PMC4979892

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HPDL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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