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Article

A novel multi-locus genetic risk score identifies patients with higher risk of generalized aggressive periodontitis.

Journal of periodontology - 1 Jul 2020

Li Wenjing, Wang Xian'e, Tian Yu, Xu Li, Zhang Li, Shi Dong, Feng Xianghui, Lu Ruifang, Meng Huanxin

Abstract excerpt

BACKGROUND: Each genetic variant individually explains only a tiny proportion of the genetic variation with insignificant predictive power. The tool of multi-locus genetic risk score (GRS), which aggregates information from multiple genetic variants, has been widely used in many complex diseases but not yet applied to generalized aggressive periodontitis (GAgP). METHODS: A total of 335 GAgP patients and 114...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31833563
DOI: 10.1002/JPER.19-0135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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